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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM2
All Species:
16.97
Human Site:
S764
Identified Species:
41.48
UniProt:
P50570
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50570
NP_001005360.1
870
98064
S764
L
Q
S
A
S
S
H
S
P
T
P
Q
R
R
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103119
870
98099
S764
L
Q
S
A
S
S
H
S
P
T
P
Q
R
R
P
Dog
Lupus familis
XP_542065
865
97464
S759
L
Q
S
T
T
S
H
S
P
T
P
Q
R
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P39054
870
98127
S764
L
Q
N
T
S
G
H
S
P
T
P
Q
R
R
P
Rat
Rattus norvegicus
P39052
870
98212
S764
L
Q
N
T
S
S
H
S
P
T
P
Q
R
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
P586
N
L
L
D
V
P
V
P
V
A
R
K
L
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
P761
L
P
S
G
L
D
N
P
R
L
S
P
P
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P39055
830
93389
L723
A
Q
K
R
E
E
M
L
R
M
Y
H
A
C
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
L675
V
R
K
N
V
E
D
L
V
P
K
A
I
M
H
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
I652
S
D
F
S
L
G
D
I
D
D
L
E
N
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
95.1
N.A.
98.1
98
N.A.
N.A.
N.A.
N.A.
32.9
N.A.
64.4
N.A.
61.9
N.A.
Protein Similarity:
100
N.A.
100
97.2
N.A.
99
99.1
N.A.
N.A.
N.A.
N.A.
51
N.A.
76.9
N.A.
76.5
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
26.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
0
0
0
0
0
10
0
10
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
0
10
0
10
20
0
10
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
20
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
20
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
50
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
0
20
0
0
0
0
0
0
0
10
10
0
0
10
% K
% Leu:
60
10
10
0
20
0
0
20
0
10
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% M
% Asn:
10
0
20
10
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
10
0
0
0
10
0
20
50
10
50
10
10
0
60
% P
% Gln:
0
60
0
0
0
0
0
0
0
0
0
50
0
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
20
0
10
0
50
50
0
% R
% Ser:
10
0
40
10
40
40
0
50
0
0
10
0
0
20
0
% S
% Thr:
0
0
0
30
10
0
0
0
0
50
0
0
0
0
0
% T
% Val:
10
0
0
0
20
0
10
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _